DNA capture using magnetic nanoparticles

Posted on Thu, Sep 22, 2016

 

Efficient methods for DNA detectionin clinical, environmental, and experimental samples are constantly in demand. In a clinical sample, DNA capture and identification can be essential to the diagnosis of disease. In public heath and environmental situations it can be used to identify contamination of food or water. DNA collection and characterization is constantly expanding our ability to answer experimental questions. DNA capture is a mainstay of modern biotechnology. Traditional techniques rely on affinity columns, centrifugation, and multiple washing steps. Newer methods are based on magnetic separation. In the beginning,magnetic separation was limitedto packing a column with magnetic material and running a solution through it. As nanotechnology evolved it became possible to use mobile solid support systems such as magnetic nanoparticles.

 

Read More

Tags: News

Magnetic particle IVD for point of care malaria diagnosis

Posted on Thu, Sep 15, 2016

 

An in vitro diagnostic product (IVD) is any reagent, device, system, or part of a system used outside of the body to diagnose a disease or infection. The IVD can be used to detect DNA/RNA, microorganisms, or protein. This can be in a laboratory setting or in a “point of care setting.” Point of care (POC) is beneficial because it removes the need to send a sample to a laboratory for testing. Therefore, the time between sample collection and diagnosis is significantly reduced. Point of care IVD is especially useful in resource-poor settings where laboratories are located far away and there is a lack of good communication or transportation infrastructure.      

Read More

Tags: News

Detection of foodborne pathogens using magnetic separation

Posted on Thu, Sep 08, 2016

 

When food becomes contaminated with pathogens it is necessary to identify the contamination and remove that food from the supply line as soon as possible. When that food is perishable it becomes all the more important to act quickly, but this demands a rapid detection system. This “need for speed” automatically eliminates the traditional culture method from the list of potential detection techniques. A commonly used method for pathogen detection is to isolate the pathogen and concentrate it enough to be accurately amplified and detected by real time quantitative polymerase chain reaction (RTqPCR). However, the method used to capture and concentrate the pathogen needs to be rapid and efficient. Magnetic nanoparticles and magnetic separation techniques are the perfect technologies for the rapid isolation and concentration of pathogens.

 

Read More

Tags: News

Sandwich hybridization DNA/RNA capture using magnetic nanoparticles

Posted on Thu, Sep 01, 2016

Read More

Tags: News

Using magnetic nanoparticles for molecular diagnosis of S. aureus

Posted on Thu, Aug 25, 2016

Read More

Tags: News

Recent advances in protein purification using biomagnetic separation - Part 2

Posted on Thu, Aug 18, 2016

Read More

Tags: News

Recent advances in protein purification using biomagnetic separation

Posted on Thu, Aug 11, 2016

Read More

Tags: News

DNA isolation from bacteria using charge-reversible magnetic nanoparticles

Posted on Thu, Aug 04, 2016

Read More

Tags: News

Magnetic bead cell separation for the detection of circulating tumor cells

Posted on Thu, Jul 28, 2016

Read More

Tags: News

Column-based magnetic activated cell sorting

Posted on Thu, Jul 21, 2016

Read More

Tags: News