Introduction
The evolution of magnetic bead technology has opened up a plethora of possibilities in the field of life sciences, spanning various applications from nucleic acid purification to protein isolation. However, the transition from research and development (R&D) to large-scale production has often been hindered by the lack of standardized tools used to separate specific proteins or molecules from a complex biomaterial. This bottleneck has posed challenges, particularly in industries such as in vitro diagnostic (IVD) reagents manufacturing and magnetic bead production, where scaling up protocols from R&D to production has been a daunting task. In this article, we explore how the standardization of magnetic bead separation conditions at the R&D level can help establish protocols built for a production level. Such standardization will aid in revolutionizing magnetic separation, ultimately simplifying and accelerating large-scale manufacturing.