Introduction
In magnetic bead separation processes, achieving reproducible and consistent outcomes can often feel like an elusive goal. Despite the promise of easier manipulation and efficient target biomolecular capture, many researchers encounter challenges such as inconsistent results, loss of beads and coupled target molecules, separation time variations, and irreversible aggregation issues. This post delves into the underlying reasons behind these roadblocks and explores solutions that can pave the way for success in magnetic bead separation protocols.