Introduction and inspiration of mRNA
There is a lot to learn from the mRNA (messenger RNA) that is present in cells, which makes up around 5% of the total RNA in cells. The presence of certain mRNA sequences can inform us about what proteins are most likely being translated at the moment so that biological processes can take place. mRNA has also emerged as a top vaccine for the novel coronavirus of 2019, also known as SARS-CoV-2. How can a messenger RNA be a vaccine you ask? mRNA works as a vaccine by providing our cells with the sequence to make the major protein found on SARS-CoV-2 called “spike” protein. Once our cells have made spike protein, our body will launch an immune response against it, and immune cells will make antibodies against the spike protein. To use and study mRNA, you must first perform mRNA isolation, which we will introduce in this article.