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Posted on Tue, Mar 15, 2011

Monitoring magnetic particle synthesis using precision magnetophoresis

magnetic separationResearchers at Centro de Fisica of the Universidade do Minho (Braga, Portugal) have used Sepmag LAB precision magnetophoresis equipment to characterize the behaviour of magnetic nanoparticle suspensions throughout their synthesis process.

In several recently published scientific papers, Dr. Maria Benelmekki and co-workers report on the effect of the stabilizing electrostatic energy on the magnetic separation process, showing that a change in the surface charge has a strong effect on the separation time of magnetic nanoparticles.

These findings are key to improve the performance of magnetic beads: future applications can be optimized by controlling each step of the synthesis monitoring magnetophoretical behaviour.

Sepmag’s systems provide homogeneous and completely reproducible biomagnetic separation conditions. These well controlled conditions, together with the possibility to monitor the process, benefit a broad range of applications.


Benelmekki, C. Caparrós, A. Montràs, R. Gonçalves, S. Lanceros-Mendez and Ll. M. Martínez. Horizontal Low Gradient Magnetophoresis behaviour of iron oxide nanclusters at the different steps of the synthesis route. J. Nanopart. Res. DOI: 10.1007/s11051-010-0218-6 (2010)

M. Benelmekki, C. Caparrós,  A. Montràs, R. Gonçalves, S. Lanceros-Mendez and Ll.M. Martínez. Contribution to the Study of Ferrite Nanobeads: Synthesis, Characterization and Investigation of Horizontal Low Gradient Magnetophoresis Behaviour. 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers. AIP Conference Proceedings, Volume 1311, 121-126 (2010)

C.C. Caparrós, M. Benelmekki, A. Montràs, S. Lanceros-Méndez and Ll. M. Martínez. Reversible aggregation and chemical resistance of magnetic nanoclusters for their recycling and repetitive use in Industrial bioprocesses.  J. Nanoscience. & Nantechnology (2011) In press.

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